Group Members
Kiel C, Yus E, Serrano L. Engineering signal transduction pathways. Cell. 2010;140(1):33-47. Abstract
Group Research Papers
Grünberg R, Burnier JV, Ferrar T, Beltran-Sastre V, Stricher F, van der Sloot AM, et al. Engineering of weak helper interactions for high-efficiency FRET probes. Nat Methods. 2013. Abstract
Janich P, Toufighi K, Solanas G, Luis N, Minkwitz S, Serrano L, et al. Human Epidermal Stem Cell Function Is Regulated by Circadian Oscillations. Cell Stem Cell. 2013. Abstract
Kiel C, Serrano L. Structural data in synthetic biology approaches for studying general design principles of cellular signaling networks. Structure. 2012;20(11):1806-13. Abstract
Yang J-, Campagna A, Delgado J, Vanhee P, Serrano L, Kiel C. SAPIN: a framework for the structural analysis of protein interaction networks. Bioinformatics. 2012;28(22):2998-9. Abstract
Kiel C, Serrano L. Challenges ahead in signal transduction: MAPK as an example. Curr Opin Biotechnol. 2012;23(3):305-14. Abstract
Kiel C, Vogt A, Campagna A, Chatr-aryamontri A, Swiatek-de Lange M, Beer M, et al. Structural and functional protein network analyses predict novel signaling functions for rhodopsin. Mol Syst Biol. 2011;7:551. Abstract
Rakoczy EP, Kiel C, McKeone R, Stricher F, Serrano L. Analysis of disease-linked rhodopsin mutations based on structure, function, and protein stability calculations. J Mol Biol. 2011;405(2):584-606. Abstract
Kiel C, Yus E, Serrano L. Engineering signal transduction pathways. Cell. 2010;140(1):33-47. Abstract
Kiel C, Serrano L. Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling. Sci Signal. 2009;2(81):ra38. Abstract
Kiel C, Filchtinski D, Spoerner M, Schreiber G, Kalbitzer H, Herrmann C. Improved binding of raf to Ras.GDP is correlated with biological activity. J Biol Chem. 2009;284(46):31893-902. Abstract
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