Group Members
Kiel C, Yus E, Serrano L. Engineering signal transduction pathways. Cell. 2010;140(1):33-47. Abstract
Group Research Papers
Kiel C, Filchtinski D, Spoerner M, Schreiber G, Kalbitzer H, Herrmann C. Improved binding of raf to Ras.GDP is correlated with biological activity. J Biol Chem. 2009;284(46):31893-902. Abstract
Kiel C, Beltrao P, Serrano L. Analyzing protein interaction networks using structural information. Annu Rev Biochem. 2008;77:415-41. Abstract
Kiel C, Aydin D, Serrano L. Association rate constants of ras-effector interactions are evolutionarily conserved. PLoS Comput Biol. 2008;4(12):e1000245. Abstract
Campagna A, Serrano L, Kiel C. Shaping dots and lines: adding modularity into protein interaction networks using structural information. FEBS Lett. 2008;582(8):1231-6. Abstract
Kiel C, Foglierini M, Kuemmerer N, Beltrao P, Serrano L. A genome-wide Ras-effector interaction network. J Mol Biol. 2007;370(5):1020-32. Abstract
Beltrao P, Kiel C, Serrano L. Structures in systems biology. Curr Opin Struct Biol. 2007;17(3):378-84. Abstract
Kiel C, Serrano L. Prediction of Ras-effector interactions using position energy matrices. Bioinformatics. 2007;23(17):2226-30. Abstract
Kiel C, Serrano L. The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes. J Mol Biol. 2006;355(4):821-44. Abstract
Wohlgemuth S, Kiel C, Krämer A, Serrano L, Wittinghofer F, Herrmann C. Recognizing and defining true Ras binding domains I: biochemical analysis. J Mol Biol. 2005;348(3):741-58. Abstract
Kiel C, Wohlgemuth S, Rousseau F, Schymkowitz J, Ferkinghoff-Borg J, Wittinghofer F, et al. Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations. J Mol Biol. 2005;348(3):759-75. Abstract
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