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  • Research Topics
    • Mycoplasma Pneumoniae
    • Cell Signaling
    • Protein Engineering
    • Synthetic Biology
    • SysteMTb
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Kiel C, Serrano L. Challenges ahead in signal transduction: MAPK as an example. Curr Opin Biotechnol. 2012;23(3):305-14. Abstract
Kiel C, Serrano L. Structural data in synthetic biology approaches for studying general design principles of cellular signaling networks. Structure. 2012;20(11):1806-13. Abstract
Yang J-, Campagna A, Delgado J, Vanhee P, Serrano L, Kiel C. SAPIN: a framework for the structural analysis of protein interaction networks. Bioinformatics. 2012;28(22):2998-9. Abstract
Rakoczy EP, Kiel C, McKeone R, Stricher F, Serrano L. Analysis of disease-linked rhodopsin mutations based on structure, function, and protein stability calculations. J Mol Biol. 2011;405(2):584-606. Abstract
Kiel C, Vogt A, Campagna A, Chatr-aryamontri A, Swiatek-de Lange M, Beer M, et al. Structural and functional protein network analyses predict novel signaling functions for rhodopsin. Mol Syst Biol. 2011;7:551. Abstract
Kiel C, Yus E, Serrano L. Engineering signal transduction pathways. Cell. 2010;140(1):33-47. Abstract
Markson G, Kiel C, Hyde R, Brown S, Charalabous P, Bremm A, et al. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Genome Res. 2009;19(10):1905-11. Abstract
Kiel C, Serrano L. Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling. Sci Signal. 2009;2(81):ra38. Abstract
Kiel C, Filchtinski D, Spoerner M, Schreiber G, Kalbitzer H, Herrmann C. Improved binding of raf to Ras.GDP is correlated with biological activity. J Biol Chem. 2009;284(46):31893-902. Abstract
Kiel C, Aydin D, Serrano L. Association rate constants of ras-effector interactions are evolutionarily conserved. PLoS Comput Biol. 2008;4(12):e1000245. Abstract
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Group Research Papers
Kiel C, Serrano L, Herrmann C. A detailed thermodynamic analysis of ras/effector complex interfaces. J Mol Biol. 2004;340(5):1039-58. Abstract
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