Research projects

Bacterial cell division

The aim of this project is study the bacterial cell division using as models Mycoplasma pneumoniae and E. coli. While the cell division operon in E.coli comprises 14 genes in mycoplasmas it comprises only four genes (mraZ, mraW, ftsA-like and ftsZ). The objective of this work is to elucidate the connection between these proteins in terms of functionality and decipher the mechanistic of the regulation of bacterial cell division.

Gene essentialness

Study the M.pneumoniae gene essentialness in different conditions. For this propose, we have designed new strategies, using new ultra-sequencing technologies.

Developing tools to manipulate M.pneumoniae

The aim of this project is to restore the double recombination in M. pneumoniae to obtain tools for engineering this microorganism.

Comparative study of M.genitalium and M.pneumoniae.

Study the transcriptome, the proteome and the DNA methylome between these two closer related species to see the conservation at level of antisense transcription and regulatory sequences. The aim of this project is study the impact of DNA methylation in the regulation of transcription and the conservation between species.