As a predoctoral student in the final year of my studies, my research has drawn on genome-wide transcriptional data surveyed in the human skin in order to study the connection between circadian rhythms and the homeostasis and differentiation of the skin.  I have also studies protein-protein interaction networks, specifically human protein complexes in order to understand the different properties of distinct classes of proteins like those are shared by several complexes as a common core and those which attach and detach from these cores as accessory proteins.

Education

Master of Science, University of Toronto, Plant Bioinformatics                                                    2006
Honours Bachelor of Science, University of Toronto, Software Engineering                                2003

Publications

1. Title: Human Epidermal Stem Cell Function Is Regulated by Circadian Oscillations

Author(s): Janich, P; Toufighi, K; Solanas, G; Luis, NM; Minkwitz, S; Serrano, L; Lehner, B; Benitah, SA
Source: CELL STEM CELL  Volume: 13 Issue: 6 Pages: 745-753  
Published: 10 OCT 2013

2. Title: Putting genetic interactions in context through a global modular decomposition 

Author(s): Bellay, J; Atluri, G; Sing, TNL; Toufighi, K; Costanzo, M; et al.
Source: GENOME RESEARCH  Volume: 21 Issue: 8 Pages: 1375-1387   
Published: 29 JUN 2011

3. Title: The Genetic Landscape of a Cell 

Author(s): Costanzo, M; Baryshnikova, A; Bellay, J; Kim, Y; Spear, ED; Sevier, CS; Ding, HM; Koh, JLY; Toufighi, K; et al.
Source: SCIENCE  Volume: 327 Issue: 5964 Pages: 425-431
Published: 22 JAN 2010

4. Title: DRYGIN: a database of quantitative genetic interaction networks in yeast 

Author(s): Koh Judice L. Y.; Ding Huiming; Costanzo Michael; Baryshnikova, A; Toufighi, K; et al.
Source: NUCLEIC ACIDS RESEARCH  Volume: 38 Supplement: 1 Pages: D502-D507  
Published: 30 OCT 2009

5. Title: Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes 

Author(s): Dixon Scott J.; Fedyshyn Yaroslav; Koh Judice L. Y.; Prasad, TSK; Chahwan, C; Chua, G; Toufighi, K; et al.
Source: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  Volume: 105 Issue: 43 Pages: 16653-16658
Published: 17 OCT 2008

6. Title: The Botany Array Resource: e-Northerns, Expression Angling, and Promoter analyses 

Author(s): Toufighi, K; Brady SM; Austin R; et al.
Source: PLANT JOURNAL  Volume: 43 Issue: 1 Pages: 153-163
Published: 10 JUN 2005